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The prevalence of HBeAg-negative chronic hepatitis B varies geographically, with a higher prevalence found in regions where patients predominantly have non-A genotype HBV. 1. Clinical algorithm for the optimal follow-up and management of patients with HBeAg-negative chronic HBV infection and normal alanine aminotransferase (ALT) activity at baseline. HBeAg-negative disease or HBeAg-negative CHB is differentiated from the inactive carrier state by the level of HBV DNA>2000 IU/ml and elevated ALT. HBeAg-Negative Hepatitis B Normally, the hepatitis B virus (HBV) needs three proteins (also called antigens) in order to manufacture more HBV. A proportion of these HBeAg-negative (mutant type CHB) patients may later develop higher levels of HBV replication and progress to HBeAg-negative chronic hepatitis. Methods:: Thirty one treatment-naīve chronic HBeAg negative HBV DNA positive hepatitis BB patients received IFN 9 MU t.i.w. combined with famciclovir 3x500 mg daily. So after that as per advice of my doctor I have created another blood report for HBeAg test and in that report I got HBeAg Negative. 3.2. Comparison between HBeAg-Negative and HBeAg-Positive Patients (Table 2) There were 25 (7.9%) HBeAg-positive patients and 290 (92.1%) HBeAg-negative patients. J Microbiol Infect Dis 2011;1(2): 58-63 Key words: Chronic hepatitis B, HBeAg negative, combination therapy, α-interferon, lamivudine HBeAg negative erişkin hastalarda... HBeAg-negative carriers with normal aminotransferase levels. , 2015; 14 (4): 470-476 471 cations of HBV infection, as are individuals who remain infected with the wild type virus... Информация взята v3.kz |
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